3,567 XNAS Volume
XNAS 18 Mar, 2025 5:30 PM (EDT)
| Client Name | Client Category | Action | Reported to Exchange | Quantity | Post Transaction Holding | Traded % | Avg. Price | Value | Security Type |
|---|---|---|---|---|---|---|---|---|---|
| Mary Beth Dooley | See Remarks below | Sale of securities on an exchange or to another person at price $ 1.33 per share. | 03 Feb 2025 | 2,107 | 13,045 (0%) | 0% | 1.3 | 2,802 | Common Stock |
| Mary Beth Dooley | Head of Finance | Sale of securities on an exchange or to another person at price $ 1.41 per share. | 29 Oct 2024 | 79 | 15,152 (0%) | 0% | 1.4 | 111 | Common Stock |
| Antoine Awad | Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 1.73 per share. | 02 Apr 2024 | 372 | 33,859 (0%) | 0% | 1.7 | 644 | Common Stock |
| Mary Beth Dooley | Head of Finance | Sale of securities on an exchange or to another person at price $ 1.73 per share. | 02 Apr 2024 | 188 | 15,231 (0%) | 0% | 1.7 | 325 | Common Stock |
| James Flynn | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Mar 2024 | 4,000 | 4,000 | - | - | Stock Option (right to buy) | |
| Barrett Peter | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2024 | 24,923 | 24,923 | - | - | Stock Option (right to buy) | |
| N. Patricia Hurter | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2024 | 14,678 | 14,678 | - | - | Stock Option (right to buy) | |
| Edward T. Mathers | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Jun 2023 | 30,000 | 30,000 | - | - | Stock Option (right to buy) | |
| Peter Barrett | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Jun 2023 | 30,000 | 30,000 | - | - | Stock Option (right to buy) | |
| Richard P. Shea | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Jun 2023 | 30,000 | 30,000 | - | - | Stock Option (right to buy) | |
| Lisa Kelly-Croswell | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Jun 2023 | 30,000 | 30,000 | - | - | Stock Option (right to buy) | |
| Michael T. Heffernan | Director | 22 Jun 2023 | 30,000 | 30,000 | - | - | Stock Option (right to buy) | ||
| Nick Leschly | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Jun 2023 | 30,000 | 30,000 | - | - | Stock Option (right to buy) | |
| Patricia N. Hurter | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Jun 2023 | 30,000 | 30,000 | - | - | Stock Option (right to buy) | |
| Michael Burgess | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Jun 2023 | 30,000 | 30,000 | - | - | Stock Option (right to buy) | |
| Aoife M. Brennan | Director, See Remarks | Sale of securities on an exchange or to another person at price $ 0.58 per share. | 03 Apr 2023 | 19,042 | 256,301 (0%) | 0% | 0.6 | 10,964 | Common Stock |
| Antoine Awad | Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 0.58 per share. | 03 Apr 2023 | 6,438 | 74,732 (0%) | 0% | 0.6 | 3,707 | Common Stock |
| Michael Jensen | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 0.58 per share. | 03 Apr 2023 | 2,553 | 46,947 (0%) | 0% | 0.6 | 1,470 | Common Stock |
| Peter Barrett | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2023 | 156,130 | 156,130 | - | - | Stock Option (right to buy) | |
| Patricia N. Hurter | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2023 | 91,954 | 91,954 | - | - | Stock Option (right to buy) | |
| Edward T. Mathers | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Jun 2022 | 27,000 | 27,000 | - | - | Stock Option (right to buy) | |
| Peter Barrett | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Jun 2022 | 27,000 | 27,000 | - | - | Stock Option (right to buy) | |
| Richard P. Shea | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Jun 2022 | 27,000 | 27,000 | - | - | Stock Option (right to buy) | |
| Lisa Kelly-Croswell | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Jun 2022 | 27,000 | 27,000 | - | - | Stock Option (right to buy) | |
| Michael T. Heffernan | Director | 09 Jun 2022 | 27,000 | 27,000 | - | - | Stock Option (right to buy) | ||
| Nick Leschly | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Jun 2022 | 27,000 | 27,000 | - | - | Stock Option (right to buy) | |
| Patricia N. Hurter | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Jun 2022 | 27,000 | 27,000 | - | - | Stock Option (right to buy) | |
| Michael Burgess | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Jun 2022 | 27,000 | 27,000 | - | - | Stock Option (right to buy) | |
| Michael Jensen | Chief Financial Officer | Purchase of securities on an exchange or from another person at price $ 1.12 per share. | 24 May 2022 | 9,500 | 39,500 (0%) | 0% | 1.1 | 10,640 | Common Stock |
| Aoife M. Brennan | Director, See Remarks | Sale of securities on an exchange or to another person at price $ 2.45 per share. | 04 Apr 2022 | 8,894 | 275,343 (0%) | 0% | 2.4 | 21,754 | Common Stock |
| Antoine Awad | Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 2.45 per share. | 04 Apr 2022 | 2,650 | 81,170 (0%) | 0% | 2.4 | 6,482 | Common Stock |
| Michael Jensen | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Mar 2022 | 230,000 | 230,000 | - | - | Stock Option (right to buy) | |
| Michael Jensen | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Mar 2022 | 30,000 | 30,000 (0%) | 0% | 0 | Common Stock | |
| Aoife M. Brennan | Director, See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Feb 2022 | 106,920 | 284,237 (0%) | 0% | 0 | Common Stock | |
| Aoife M. Brennan | Director, See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Feb 2022 | 434,160 | 434,160 | - | - | Stock Option (right to buy) | |
| Antoine Awad | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Feb 2022 | 40,820 | 83,820 (0%) | 0% | 0 | Common Stock | |
| Antoine Awad | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Feb 2022 | 165,490 | 165,490 | - | - | Stock Option (right to buy) | |
| Peter Barrett | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2022 | 49,334 | 49,334 | - | - | Stock Option (right to buy) | |
| Chau Q. Khuong | Director | Grant, award, or other acquisition of securities at price $ 3.00 per share. | 20 Apr 2021 | 1,666,666 | 3,696,662 (11%) | 5% | 3 | 4,999,998 | Common Stock, $0.001 par value |
| Aoife M. Brennan | Director, See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Mar 2021 | 71,250 | 177,317 (0%) | 0% | 0 | Common Stock | |
| Aoife M. Brennan | Director, See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Mar 2021 | 285,000 | 285,000 | - | - | Stock Option (right to buy) | |
| Richard Riese | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Mar 2021 | 17,500 | 39,000 (0%) | 0% | 0 | Common Stock | |
| Richard Riese | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Mar 2021 | 70,000 | 70,000 | - | - | Stock Option (right to buy) | |
| Antoine Awad | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Mar 2021 | 17,500 | 43,000 (0%) | 0% | 0 | Common Stock | |
| Antoine Awad | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Mar 2021 | 70,000 | 70,000 | - | - | Stock Option (right to buy) | |
| Lisa Kelly-Croswell | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Feb 2021 | 30,000 | 30,000 | - | - | Stock Option (right to buy) | |
| Peter Barrett | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2021 | 57,498 | 57,498 | - | - | Stock Option (right to buy) | |
| Peter Barrett | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Jul 2020 | 1,541 | 1,541 | - | - | Stock Option (right to buy) | |
| Edward T. Mathers | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jun 2020 | 15,000 | 15,000 | - | - | Stock Option (right to buy) | |
| Peter Barrett | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jun 2020 | 15,000 | 15,000 | - | - | Stock Option (right to buy) | |
| Richard P. Shea | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jun 2020 | 15,000 | 15,000 | - | - | Stock Option (right to buy) | |
| Nick Leschly | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jun 2020 | 15,000 | 15,000 | - | - | Stock Option (right to buy) | |
| Chau Q. Khuong | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jun 2020 | 15,000 | 15,000 | - | - | Stock Option (right to buy) | |
| Patricia N. Hurter | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jun 2020 | 15,000 | 15,000 | - | - | Stock Option (right to buy) | |
| Michael Burgess | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jun 2020 | 15,000 | 15,000 | - | - | Stock Option (right to buy) | |
| Aoife M. Brennan | Director, See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Mar 2020 | 185,300 | 185,300 | - | - | Stock Option (right to buy) | |
| Aoife M. Brennan | Director, See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Mar 2020 | 46,300 | 106,067 (0%) | 0% | 0 | Common Stock | |
| Richard Riese | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Mar 2020 | 54,000 | 54,000 | - | - | Stock Option (right to buy) | |
| Richard Riese | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Mar 2020 | 13,500 | 21,500 (0%) | 0% | 0 | Common Stock | |
| Peter Barrett | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2020 | 48,656 | 48,656 | - | - | Stock Option (right to buy) | |
| Richard Riese | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Dec 2019 | 150,000 | 150,000 | - | - | Stock Option (right to buy) | |
| Richard P. Shea | Director | Purchase of securities on an exchange or from another person at price $ 2.74 per share. | 13 Dec 2019 | 7,500 | 7,500 (0%) | 0% | 2.7 | 20,550 | Common Stock |
| Gregg Beloff | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Oct 2019 | 50,000 | 50,000 | - | - | Stock Option (right to buy) | |
| Aoife M. Brennan | Director, See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Sep 2019 | 8,000 | 59,767 (0%) | 0% | 0 | Common Stock | |
| Scott Eric Plevy | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Sep 2019 | 8,000 | 8,000 (0%) | 0% | 0 | Common Stock | |
| Richard Riese | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Sep 2019 | 8,000 | 8,000 (0%) | 0% | 0 | Common Stock | |
| Scott Eric Plevy | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Jun 2019 | 150,000 | 150,000 | - | - | Stock Option (right to buy) | |
| Michael F. Powell | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jun 2019 | 10,000 | 10,000 | - | - | Stock Option (right to buy) | |
| Peter Barrett | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jun 2019 | 10,000 | 10,000 | - | - | Stock Option (right to buy) | |
| Richard P. Shea | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jun 2019 | 10,000 | 10,000 | - | - | Stock Option (right to buy) | |
| Nick Leschly | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jun 2019 | 10,000 | 10,000 | - | - | Stock Option (right to buy) | |
| Chau Q. Khuong | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jun 2019 | 10,000 | 10,000 | - | - | Stock Option (right to buy) | |
| Patricia N. Hurter | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jun 2019 | 10,000 | 10,000 | - | - | Stock Option (right to buy) | |
| Todd E. Shegog | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Mar 2019 | 58,500 | 58,500 | - | - | Stock Option (right to buy) | |
| Aoife M. Brennan | Director, See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Mar 2019 | 185,000 | 185,000 | - | - | Stock Option (right to buy) | |
| Paul Francis Miller | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 9.75 per share. | 12 Feb 2019 | 5,849 | 48,135 (0%) | 0% | 9.8 | 57,028 | Common Stock |
| Paul Francis Miller | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 9.75 per share. | 12 Feb 2019 | 3,151 | 53,984 (0%) | 0% | 9.7 | 30,722 | Common Stock |
| Patricia N. Hurter | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Feb 2019 | 20,000 | 20,000 | - | - | Stock Option (right to buy) | |
| Peter Barrett | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2019 | 17,380 | 17,380 | - | - | Stock Option (right to buy) | |
| Aoife M. Brennan | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Oct 2018 | 150,000 | 150,000 | - | - | Stock Option (right to buy) | |
| Paul Francis Miller | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 9.77 per share. | 18 Oct 2018 | 3,000 | 57,135 (0%) | 0% | 9.8 | 29,296 | Common Stock |
| Paul Francis Miller | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 13.05 per share. | 18 Sep 2018 | 3,000 | 60,135 (0%) | 0% | 13.1 | 39,163 | Common Stock |
| Paul Francis Miller | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 12.54 per share. | 05 Sep 2018 | 3,000 | 63,135 (0%) | 0% | 12.5 | 37,635 | Common Stock |
| Paul Francis Miller | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 9.77 per share. | 29 Aug 2018 | 1,658 | 67,477 (0%) | 0% | 9.8 | 16,198 | Common Stock |
| Paul Francis Miller | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 9.76 per share. | 29 Aug 2018 | 1,342 | 66,135 (0%) | 0% | 9.8 | 13,092 | Common Stock |
| Paul Francis Miller | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 11.01 per share. | 18 Jul 2018 | 3,000 | 69,135 (0%) | 0% | 11.0 | 33,022 | Common Stock |
| Paul Francis Miller | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 9.75 per share. | 19 Jun 2018 | 946 | 74,189 (0%) | 0% | 9.8 | 9,224 | Common Stock |
| Paul Francis Miller | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 9.75 per share. | 19 Jun 2018 | 1,000 | 72,135 (0%) | 0% | 9.8 | 9,750 | Common Stock |
| Paul Francis Miller | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 9.80 per share. | 19 Jun 2018 | 1,054 | 72,135 (0%) | 0% | 9.8 | 10,329 | Common Stock |
| Edward T. Mathers | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jun 2018 | 10,000 | 10,000 | - | - | Stock Option (right to buy) | |
| Michael F. Powell | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jun 2018 | 10,000 | 10,000 | - | - | Stock Option (right to buy) | |
| Peter Barrett | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jun 2018 | 10,000 | 10,000 | - | - | Stock Option (right to buy) | |
| Richard P. Shea | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jun 2018 | 10,000 | 10,000 | - | - | Stock Option (right to buy) | |
| Nick Leschly | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jun 2018 | 10,000 | 10,000 | - | - | Stock Option (right to buy) | |
| Chau Q. Khuong | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jun 2018 | 10,000 | 10,000 | - | - | Stock Option (right to buy) | |
| Aoife M. Brennan | Interim President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jun 2018 | 54,000 | 54,000 | - | - | Stock Option (right to buy) | |
| Andrew Gengos | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2018 | 10,000 | 10,000 | - | - | Stock Option (right to buy) | |
| Jose-Carlos Gutierrez-Ramos | Director, See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2018 | 120,540 | 120,540 | - | - | Stock Option (right to buy) | |
| Todd Shegog | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2018 | 48,000 | 48,000 | - | - | Stock Option (right to buy) | |
| Aoife M. Brennan | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2018 | 56,000 | 56,000 | - | - | Stock Option (right to buy) | |
| Paul Francis Miller | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2018 | 16,000 | 16,000 | - | - | Stock Option (right to buy) | |
| Anthony A. Florence | Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 9.75 per share. | 26 Jan 2018 | 410,000 | 4,228,940 (19%) | 1% | 9.8 | 3,997,500 | Common Stock |
| M. James Barrett | Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 9.75 per share. | 26 Jan 2018 | 410,000 | 4,228,940 (19%) | 1% | 9.8 | 3,997,500 | Common Stock |
| Michael F. Powell | None | Grant, award, or other acquisition of securities at price $ 9.75 per share. | 26 Jan 2018 | 150,000 | 574,972 (2%) | 0% | 9.8 | 1,462,500 | Common Stock |
| Peter J. Barris | Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 9.75 per share. | 26 Jan 2018 | 410,000 | 4,228,940 (19%) | 1% | 9.8 | 3,997,500 | Common Stock |
| David M. Mott | Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 9.75 per share. | 26 Jan 2018 | 410,000 | 4,228,940 (19%) | 1% | 9.8 | 3,997,500 | Common Stock |
| Sandell D Scott | Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 9.75 per share. | 26 Jan 2018 | 410,000 | 4,228,940 (19%) | 1% | 9.8 | 3,997,500 | Common Stock |
| Forest Baskett | Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 9.75 per share. | 26 Jan 2018 | 410,000 | 4,228,940 (19%) | 1% | 9.8 | 3,997,500 | Common Stock |
| Patrick J. Kerins | Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 9.75 per share. | 26 Jan 2018 | 410,000 | 4,228,940 (19%) | 1% | 9.8 | 3,997,500 | Common Stock |
| Ravi Viswanathan | Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 9.75 per share. | 26 Jan 2018 | 410,000 | 4,228,940 (19%) | 1% | 9.8 | 3,997,500 | Common Stock |
| Chau Q. Khuong | None | Grant, award, or other acquisition of securities at price $ 9.75 per share. | 26 Jan 2018 | 715,000 | 2,029,996 (9%) | 3% | 9.8 | 6,971,250 | Common Stock |
| Peter Sonsini | Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 9.75 per share. | 26 Jan 2018 | 410,000 | 4,228,940 (19%) | 1% | 9.8 | 3,997,500 | Common Stock |
| Jose-Carlos Gutierrez-Ramos | Director, See Remarks | Gift of securities by or to the insider at price $ 0.00 per share. | 31 Dec 2017 | 10,000 | 352,619 (2%) | 0% | 0 | Common Stock | |
| Edward T. Mathers | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Dec 2017 | 18,572 | 18,572 | - | - | Stock Option (right to buy) | |
| Michael F. Powell | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Dec 2017 | 18,572 | 18,572 | - | - | Stock Option (right to buy) | |
| Peter Barrett | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Dec 2017 | 11,570 | 11,570 | - | - | Stock Option (right to buy) | |
| Peter Barrett | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Dec 2017 | 17,143 | 17,143 | - | - | Stock Option (right to buy) | |
| Richard P. Shea | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Dec 2017 | 17,143 | 17,143 | - | - | Stock Option (right to buy) | |
| Nick Leschly | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Dec 2017 | 17,143 | 17,143 | - | - | Stock Option (right to buy) | |
| Chau Q. Khuong | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Dec 2017 | 17,143 | 17,143 | - | - | Stock Option (right to buy) | |
| Andrew Gengos | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Oct 2017 | 154,000 | 154,000 | - | - | Stock Option (right to buy) | |
| Anthony A. Florence | Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Aug 2017 | 3,394,439 | 3,818,940 (23%) | 20% | 0 | Common Stock | |
| Edward T. Mathers | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Aug 2017 | 1,428 | 1,428 | - | - | Stock Option (right to buy) | |
| M. James Barrett | Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Aug 2017 | 3,394,439 | 3,818,940 (23%) | 20% | 0 | Common Stock | |
| Michael F. Powell | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Aug 2017 | 1,428 | 1,428 | - | - | Stock Option (right to buy) | |
| Peter J. Barris | Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Aug 2017 | 3,394,439 | 3,818,940 (23%) | 20% | 0 | Common Stock | |
| Peter Barrett | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Aug 2017 | 2,857 | 2,857 | - | - | Stock Option (right to buy) | |
| Richard P. Shea | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Aug 2017 | 2,857 | 2,857 | - | - | Stock Option (right to buy) | |
| David M. Mott | Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Aug 2017 | 3,394,439 | 3,818,940 (23%) | 20% | 0 | Common Stock | |
| Sandell D Scott | Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Aug 2017 | 3,394,439 | 3,818,940 (23%) | 20% | 0 | Common Stock | |
| Forest Baskett | Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Aug 2017 | 3,394,439 | 3,818,940 (23%) | 20% | 0 | Common Stock | |
| Patrick J. Kerins | Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Aug 2017 | 3,394,439 | 3,818,940 (23%) | 20% | 0 | Common Stock | |
| Ravi Viswanathan | Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Aug 2017 | 3,394,439 | 3,818,940 (23%) | 20% | 0 | Common Stock | |
| Nick Leschly | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Aug 2017 | 2,857 | 2,857 | - | - | Stock Option (right to buy) | |
| Chau Q. Khuong | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Aug 2017 | 2,857 | 2,857 | - | - | Stock Option (right to buy) | |
| Peter Sonsini | Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Aug 2017 | 3,394,439 | 3,818,940 (23%) | 20% | 0 | Common Stock | |
| Jon Irvin | Vice President, Finance | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 01 Dec 2016 | 280 | 7,625 | - | - | Common Stock | |
| Jon Irvin | Vice President, Finance | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 11 Nov 2016 | 150 | 7,905 | - | - | Common Stock | |
| Jon Irvin | Vice President, Finance | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 01 Nov 2016 | 280 | 8,055 | - | - | Common Stock | |
| Jon Irvin | Vice President, Finance | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 11 Oct 2016 | 150 | 8,335 | - | - | Common Stock | |
| Jon Irvin | Vice President, Finance | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 03 Oct 2016 | 250 | 8,485 | - | - | Common Stock | |
| Clay B. Siegall | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Jun 2016 | 10,000 | 10,000 | - | - | Stock Option (Right to Buy) | |
| Michael F. Powell | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Jun 2016 | 10,000 | 10,000 | - | - | Stock Option (Right to Buy) | |
| Edward T. Mathers | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Jun 2016 | 10,000 | 10,000 | - | - | Stock Option (Right to Buy) | |
| Peter Lichtlen | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Jun 2016 | 10,000 | 10,000 | - | - | Stock Option (Right to Buy) | |
| Lawrence M. Alleva | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Jun 2016 | 10,000 | 10,000 | - | - | Stock Option (Right to Buy) | |
| Matthew Winkler | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Jun 2016 | 10,000 | 10,000 | - | - | Stock Option (Right to Buy) | |
| Perry Nisen | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Jun 2016 | 20,000 | 20,000 | - | - | Stock Option (Right to Buy) | |
| Vincent O'Neill | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Apr 2016 | 250,000 | 250,000 | - | - | Stock Option (Right to Buy) | |
| Alan Fuhrman | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Mar 2016 | 60,000 | 60,000 | - | - | Stock Option (Right to Buy) | |
| Paul Lammers | Director, President & CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Mar 2016 | 165,000 | 165,000 | - | - | Stock Option (Right to Buy) | |
| Peter Lichtlen | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Mar 2016 | 8,000 | 8,000 | - | - | Stock Option (Right to Buy) | |
| Jon Irvin | Vice President, Finance | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Mar 2016 | 10,000 | 10,000 | - | - | Stock Option (Right to Buy) | |
| Casi DeYoung | Chief Business Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Mar 2016 | 60,000 | 60,000 | - | - | Stock Option (Right to Buy) | |
| Peter Lichtlen | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2016 | 12,000 | 12,000 | - | - | Stock Option (Right to Buy) | |
| James I. Healy | Ten Percent Owner | 05 Oct 2015 | 1,244,269 | 0 | - | - | Series C Preferred Stock | ||
| James I. Healy | Ten Percent Owner | 05 Oct 2015 | 583,559 | 0 | - | - | Series D Preferred Stock | ||
| James I. Healy | Ten Percent Owner | 05 Oct 2015 | 1,244,269 | 1,244,269 | - | - | Common Stock | ||
| James I. Healy | Ten Percent Owner | 05 Oct 2015 | 583,559 | 1,827,828 | - | - | Common Stock | ||
| James I. Healy | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 05 Oct 2015 | 289,841 | 2,117,669 | - | - | Common Stock | |
| James I. Healy | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 05 Oct 2015 | 857,142 | 2,974,811 | - | - | Common Stock | |
| Anthony A. Florence | Ten Percent Owner | 05 Oct 2015 | 1,241,650 | 0 | - | - | Series C Preferred Stock | ||
| Anthony A. Florence | Ten Percent Owner | 05 Oct 2015 | 583,559 | 0 | - | - | Series D Preferred Stock | ||
| Anthony A. Florence | Ten Percent Owner | 05 Oct 2015 | 1,241,650 | 1,241,650 | - | - | Common Stock | ||
| Anthony A. Florence | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 05 Oct 2015 | 257,516 | 1,499,166 | - | - | Common Stock | |
| Anthony A. Florence | Ten Percent Owner | 05 Oct 2015 | 583,559 | 2,082,725 | - | - | Common Stock | ||
| Anthony A. Florence | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 05 Oct 2015 | 31,650 | 2,114,375 | - | - | Common Stock | |
| Anthony A. Florence | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 05 Oct 2015 | 857,142 | 2,971,517 | - | - | Common Stock | |
| David M. Mott | Ten Percent Owner | 05 Oct 2015 | 1,241,650 | 0 | - | - | Series C Preferred Stock | ||
| David M. Mott | Ten Percent Owner | 05 Oct 2015 | 583,559 | 0 | - | - | Series D Preferred Stock | ||
| David M. Mott | Ten Percent Owner | 05 Oct 2015 | 1,241,650 | 1,241,650 | - | - | Common Stock | ||
| David M. Mott | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 05 Oct 2015 | 257,516 | 1,499,166 | - | - | Common Stock | |
| David M. Mott | Ten Percent Owner | 05 Oct 2015 | 583,559 | 2,082,725 | - | - | Common Stock | ||
| David M. Mott | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 05 Oct 2015 | 31,650 | 2,114,375 | - | - | Common Stock | |
| David M. Mott | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 05 Oct 2015 | 857,142 | 2,971,517 | - | - | Common Stock | |
| M. James Barrett | Ten Percent Owner | 05 Oct 2015 | 1,241,650 | 0 | - | - | Series C Preferred Stock | ||
| M. James Barrett | Ten Percent Owner | 05 Oct 2015 | 583,559 | 0 | - | - | Series D Preferred Stock | ||
| M. James Barrett | Ten Percent Owner | 05 Oct 2015 | 1,241,650 | 1,241,650 | - | - | Common Stock | ||
| M. James Barrett | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 05 Oct 2015 | 257,516 | 1,499,166 | - | - | Common Stock | |
| M. James Barrett | Ten Percent Owner | 05 Oct 2015 | 583,559 | 2,082,725 | - | - | Common Stock | ||
| M. James Barrett | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 05 Oct 2015 | 31,650 | 2,114,375 | - | - | Common Stock | |
| M. James Barrett | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 05 Oct 2015 | 857,142 | 2,971,517 | - | - | Common Stock | |
| Michael F. Powell | Director, Ten Percent Owner | 05 Oct 2015 | 1,244,269 | 0 | - | - | Series C Preferred Stock | ||
| Michael F. Powell | Director, Ten Percent Owner | 05 Oct 2015 | 583,559 | 0 | - | - | Series D Preferred Stock | ||
| Michael F. Powell | Director, Ten Percent Owner | 05 Oct 2015 | 1,244,269 | 1,244,269 | - | - | Common Stock | ||
| Michael F. Powell | Director, Ten Percent Owner | 05 Oct 2015 | 583,559 | 1,827,828 | - | - | Common Stock | ||
| Michael F. Powell | Director, Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 05 Oct 2015 | 289,841 | 2,117,669 | - | - | Common Stock | |
| Michael F. Powell | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 05 Oct 2015 | 857,142 | 2,974,811 | - | - | Common Stock | |
| Forest Baskett | Ten Percent Owner | 05 Oct 2015 | 1,241,650 | 0 | - | - | Series C Preferred Stock | ||
| Forest Baskett | Ten Percent Owner | 05 Oct 2015 | 583,559 | 0 | - | - | Series D Preferred Stock | ||
| Forest Baskett | Ten Percent Owner | 05 Oct 2015 | 1,241,650 | 1,241,650 | - | - | Common Stock | ||
| Forest Baskett | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 05 Oct 2015 | 257,516 | 1,499,166 | - | - | Common Stock | |
| Forest Baskett | Ten Percent Owner | 05 Oct 2015 | 583,559 | 2,082,725 | - | - | Common Stock | ||
| Forest Baskett | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 05 Oct 2015 | 31,650 | 2,114,375 | - | - | Common Stock | |
| Forest Baskett | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 05 Oct 2015 | 857,142 | 2,971,517 | - | - | Common Stock | |
| Krishna Kolluri | Ten Percent Owner | 05 Oct 2015 | 1,241,650 | 0 | - | - | Series C Preferred Stock | ||
| Krishna Kolluri | Ten Percent Owner | 05 Oct 2015 | 583,559 | 0 | - | - | Series D Preferred Stock | ||
| Krishna Kolluri | Ten Percent Owner | 05 Oct 2015 | 1,241,650 | 1,241,650 | - | - | Common Stock | ||
| Krishna Kolluri | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 05 Oct 2015 | 257,516 | 1,499,166 | - | - | Common Stock | |
| Krishna Kolluri | Ten Percent Owner | 05 Oct 2015 | 583,559 | 2,082,725 | - | - | Common Stock | ||
| Krishna Kolluri | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 05 Oct 2015 | 31,650 | 2,114,375 | - | - | Common Stock | |
| Krishna Kolluri | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 05 Oct 2015 | 857,142 | 2,971,517 | - | - | Common Stock | |
| Peter J. Barris | Ten Percent Owner | 05 Oct 2015 | 1,241,650 | 0 | - | - | Series C Preferred Stock | ||
| Peter J. Barris | Ten Percent Owner | 05 Oct 2015 | 583,559 | 0 | - | - | Series D Preferred Stock | ||
| Peter J. Barris | Ten Percent Owner | 05 Oct 2015 | 1,241,650 | 1,241,650 | - | - | Common Stock | ||
| Peter J. Barris | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 05 Oct 2015 | 257,516 | 1,499,166 | - | - | Common Stock | |
| Peter J. Barris | Ten Percent Owner | 05 Oct 2015 | 583,559 | 2,082,725 | - | - | Common Stock | ||
| Peter J. Barris | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 05 Oct 2015 | 31,650 | 2,114,375 | - | - | Common Stock | |
| Peter J. Barris | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 05 Oct 2015 | 857,142 | 2,971,517 | - | - | Common Stock | |
| Harry R. Weller | Ten Percent Owner | 05 Oct 2015 | 1,241,650 | 0 | - | - | Series C Preferred Stock | ||
| Harry R. Weller | Ten Percent Owner | 05 Oct 2015 | 583,559 | 0 | - | - | Series D Preferred Stock | ||
| Harry R. Weller | Ten Percent Owner | 05 Oct 2015 | 1,241,650 | 1,241,650 | - | - | Common Stock | ||
| Harry R. Weller | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 05 Oct 2015 | 257,516 | 1,499,166 | - | - | Common Stock | |
| Harry R. Weller | Ten Percent Owner | 05 Oct 2015 | 583,559 | 2,082,725 | - | - | Common Stock | ||
| Harry R. Weller | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 05 Oct 2015 | 31,650 | 2,114,375 | - | - | Common Stock | |
| Harry R. Weller | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 05 Oct 2015 | 857,142 | 2,971,517 | - | - | Common Stock | |
| Patrick J. Kerins | Ten Percent Owner | 05 Oct 2015 | 1,241,650 | 0 | - | - | Series C Preferred Stock | ||
| Patrick J. Kerins | Ten Percent Owner | 05 Oct 2015 | 583,559 | 0 | - | - | Series D Preferred Stock | ||
| Patrick J. Kerins | Ten Percent Owner | 05 Oct 2015 | 1,241,650 | 1,241,650 | - | - | Common Stock | ||
| Patrick J. Kerins | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 05 Oct 2015 | 257,516 | 1,499,166 | - | - | Common Stock | |
| Patrick J. Kerins | Ten Percent Owner | 05 Oct 2015 | 583,559 | 2,082,725 | - | - | Common Stock | ||
| Patrick J. Kerins | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 05 Oct 2015 | 31,650 | 2,114,375 | - | - | Common Stock | |
| Patrick J. Kerins | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 05 Oct 2015 | 857,142 | 2,971,517 | - | - | Common Stock | |
| Sandell D Scott | Ten Percent Owner | 05 Oct 2015 | 1,241,650 | 0 | - | - | Series C Preferred Stock | ||
| Sandell D Scott | Ten Percent Owner | 05 Oct 2015 | 583,559 | 0 | - | - | Series D Preferred Stock | ||
| Sandell D Scott | Ten Percent Owner | 05 Oct 2015 | 1,241,650 | 1,241,650 | - | - | Common Stock | ||
| Sandell D Scott | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 05 Oct 2015 | 257,516 | 1,499,166 | - | - | Common Stock | |
| Sandell D Scott | Ten Percent Owner | 05 Oct 2015 | 583,559 | 2,082,725 | - | - | Common Stock | ||
| Sandell D Scott | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 05 Oct 2015 | 31,650 | 2,114,375 | - | - | Common Stock | |
| Sandell D Scott | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 05 Oct 2015 | 857,142 | 2,971,517 | - | - | Common Stock | |
| Ravi Viswanathan | Ten Percent Owner | 05 Oct 2015 | 1,241,650 | 0 | - | - | Series C Preferred Stock | ||
| Ravi Viswanathan | Ten Percent Owner | 05 Oct 2015 | 583,559 | 0 | - | - | Series D Preferred Stock | ||
| Ravi Viswanathan | Ten Percent Owner | 05 Oct 2015 | 1,241,650 | 1,241,650 | - | - | Common Stock | ||
| Ravi Viswanathan | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 05 Oct 2015 | 257,516 | 1,499,166 | - | - | Common Stock | |
| Ravi Viswanathan | Ten Percent Owner | 05 Oct 2015 | 583,559 | 2,082,725 | - | - | Common Stock | ||
| Ravi Viswanathan | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 05 Oct 2015 | 31,650 | 2,114,375 | - | - | Common Stock | |
| Ravi Viswanathan | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 05 Oct 2015 | 857,142 | 2,971,517 | - | - | Common Stock | |
| Lawrence M. Alleva | None | 05 Oct 2015 | 3,818 | 0 | - | - | Series D Preferred Stock | ||
| Lawrence M. Alleva | None | 05 Oct 2015 | 3,818 | 3,818 | - | - | Common Stock | ||
| Lawrence M. Alleva | None | Other type of transaction at price $ 0.00 per share. | 05 Oct 2015 | 207 | 4,025 | - | - | Common Stock | |
| Matthew Winkler | None | 05 Oct 2015 | 134,958 | 0 | - | - | Series A Preferred Stock | ||
| Matthew Winkler | None | 05 Oct 2015 | 2,345 | 0 | - | - | Series A Preferred Stock | ||
| Matthew Winkler | None | 05 Oct 2015 | 2,345 | 0 | - | - | Series A Preferred Stock | ||
| Matthew Winkler | None | 05 Oct 2015 | 2,345 | 0 | - | - | Series A Preferred Stock | ||
| Matthew Winkler | None | 05 Oct 2015 | 28,458 | 0 | - | - | Series B Preferred Stock | ||
| Matthew Winkler | None | 05 Oct 2015 | 235,899 | 0 | - | - | Series C Preferred Stock | ||
| Matthew Winkler | None | 05 Oct 2015 | 40,281 | 0 | - | - | Series C Preferred Stock | ||
| Matthew Winkler | None | 05 Oct 2015 | 40,281 | 0 | - | - | Series C Preferred Stock | ||
| Matthew Winkler | None | 05 Oct 2015 | 40,281 | 0 | - | - | Series C Preferred Stock | ||
| Matthew Winkler | None | 05 Oct 2015 | 187,277 | 0 | - | - | Series D Preferred Stock | ||
| Matthew Winkler | None | 05 Oct 2015 | 134,958 | 134,958 | - | - | Common Stock | ||
| Matthew Winkler | None | 05 Oct 2015 | 28,458 | 163,416 | - | - | Common Stock | ||
| Matthew Winkler | None | 05 Oct 2015 | 235,899 | 399,315 | - | - | Common Stock | ||
| Matthew Winkler | None | 05 Oct 2015 | 187,277 | 586,592 | - | - | Common Stock | ||
| Matthew Winkler | None | 05 Oct 2015 | 2,345 | 2,345 | - | - | Common Stock | ||
| Matthew Winkler | None | 05 Oct 2015 | 40,281 | 42,626 | - | - | Common Stock | ||
| Matthew Winkler | None | 05 Oct 2015 | 2,345 | 2,345 | - | - | Common Stock | ||
| Matthew Winkler | None | 05 Oct 2015 | 40,281 | 42,626 | - | - | Common Stock | ||
| Matthew Winkler | None | 05 Oct 2015 | 2,345 | 2,345 | - | - | Common Stock | ||
| Matthew Winkler | None | 05 Oct 2015 | 40,281 | 42,626 | - | - | Common Stock | ||
| Matthew Winkler | None | Other type of transaction at price $ 0.00 per share. | 05 Oct 2015 | 62,582 | 649,174 | - | - | Common Stock | |
| Matthew Winkler | None | Other type of transaction at price $ 0.00 per share. | 05 Oct 2015 | 8,408 | 51,034 | - | - | Common Stock | |
| Matthew Winkler | None | Other type of transaction at price $ 0.00 per share. | 05 Oct 2015 | 8,408 | 51,034 | - | - | Common Stock | |
| Matthew Winkler | None | Other type of transaction at price $ 0.00 per share. | 05 Oct 2015 | 8,408 | 51,034 | - | - | Common Stock | |
| Clay B. Siegall | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Sep 2015 | 12,000 | 12,000 | - | - | Stock Option (Right to Buy) | |
| Michael F. Powell | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Sep 2015 | 7,200 | 7,200 | - | - | Stock Option (Right to Buy) | |
| Alan Fuhrman | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Sep 2015 | 167,180 | 167,180 | - | - | Stock Option (Right to Buy) | |
| Edward T. Mathers | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Sep 2015 | 7,200 | 7,200 | - | - | Stock Option (Right to Buy) | |
| Paul Lammers | Director, President & CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Sep 2015 | 76,666 | 76,666 | - | - | Stock Option (Right to Buy) | |
| Jones V Elaine | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Sep 2015 | 7,200 | 7,200 | - | - | Stock Option (Right to Buy) | |
| Lawrence M. Alleva | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Sep 2015 | 10,533 | 10,533 | - | - | Stock Option (Right to Buy) | |
| Jon Irvin | Vice President, Finance | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Sep 2015 | 25,000 | 25,000 | - | - | Stock Option (Right to Buy) | |
| Sinil Kim | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Sep 2015 | 25,000 | 25,000 | - | - | Stock Option (Right to Buy) | |
| Casi DeYoung | Chief Business Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Sep 2015 | 26,666 | 26,666 | - | - | Stock Option (Right to Buy) | |
| Miguel Barbosa | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Sep 2015 | 284,206 | 284,206 | - | - | Stock Option (Right to Buy) | |
| Matthew Winkler | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Sep 2015 | 7,200 | 7,200 | - | - | Stock Option (Right to Buy) |